Pharmacy
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General Introduction Information of the Course

Course Code:

MED118

Ders İsmi:

Medical Biology and Genetics

Ders Yarıyılı:

Spring

Ders Kredileri:

Theoretical	Practical	Credit	ECTS
2	0	2	3

Language of instruction:

Ders Koşulu:

Ders İş Deneyimini Gerektiriyor mu?:

Type of course:

Necessary

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi Figen ABATAY SEL

Course Lecturer(s):

Öğretim Elemanı
Dr. Pelin DİLSİZ ERİM
Asuman ÇELEBİ
Neşe AYŞİT
Dr.Öğr.Üyesi Derya DİLEK KANÇAĞI
Dr.Öğr.Üyesi Figen ABATAY SEL

Course Assistants:

Course Objectives and Content

Course Objectives:

This course aims to provide a prespective about medical biology as well as cellular processes and genetic mechanisms. It aims to provide a broad perspective to life sciences with its cell biology, molecular biology and molecular genetics perspective.

Course Content:

This course; Introduction to medical biology and genetics course, establishing the relationship between course learning outcomes and program competencies Introduction to medical biology, the beginning of life, common characteristics, cell diversity, prokaryotic and eukaryotic cell differences, cell theory, cell and organelles, cell membrane, endosymbiotic theory, cytoskeleton, movement and substance transport, cell cycle and control, cell division, mitosis, meiosis, basic concepts in genetics, nucleic acids: DNA and RNA, DNA replication, transcription, post-transcriptional modifications, translation, post-translational modifications, protein synthesis and packaging, gene It covers the regulation of expression, DNA sequences and chromosome structure, DNA damage, DNA mutations and varieties, DNA damage repair mechanisms, genetic diseases, molecular biology techniques, stem cell biology, human genome project, cancer genetics and epigenetic mechanisms.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) To be able to define concepts related to cell types, cell structure and organelles
2) Identifying DNA damage, cell aging and cancer
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) To be able to explain basic concepts in genetics, genetic material, transcription and translation
2) Ability to explain the relationship between inheritance forms, chromosomal structure and number anomalies and genetic diseases
3) To be able to explain the human genome project, cancer genetics and stem cell biology
4) To be able to explain epigenetic mechanisms
Field Specific Competence
Competence to Work Independently and Take Responsibility

Course Weekly Plan

Week	Subject	Related Preparation
1)	Introduction to Medical Biology. Living science. Prokaryotic and eukaryotic organisms, viruses. Cell, cell theory, organelles	1. Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri
2)	Cell, cell theory and organelles	2. Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
3)	Cell membrane in prokaryotic and eukaryotic organisms. Cell wall in bacteria.	Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
4)	Cell skeleton. Cell cycle	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri
5)	Basic concepts in genetic. DNA, chromatin, chromosome and gene concepts. RNA varieties.	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri
6)	Structure of DNA and RNA	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
7)	Central dogma. Replication. In vitro DNA synthesis. Polymerase chain reaction.	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
8)	Midterm exams
9)	Transcription	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
10)	Translation. Protein Structure and Stability	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
11)	Regulation of gene expression. Epigenetic mechanisms.	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
12)	DNA damage, chromosomal disorders. Genetic factors in disease formation. Genetic diseases. Damage repair mechanisms. Mutation and mutation types	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
13)	Stem cell biology	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
14)	Cancer genetics	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
15)	Mutation and mutation types. Chromosomal anomalies and diseases	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013
16)	Final Exam

Sources

Course Notes / Textbooks:	Chandar, N., Viselli, S., & Yanık, B. (2012). Hücre ve moleküler biyoloji. Nobel Tıp Kitabevleri
References:	Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013

Relationship Between Course and Program Learning Outcomes

Course Learning Outcomes	1	5	2	3	4	6
Program Outcomes
1) To have knowledge and application skills about pre-formulation, formulation, laboratory, pilot and industrial scale production, quality assurance, quality control, validation, stability, storage, bioavailability, bioequivalence, licensing and patent studies of natural, synthetic, biological, biotechnological, nanotechnological, cosmetic, dermocosmetic products.
2) To have basic information about diseases, the stages of all drugs in the body, their mechanism of action, undesirable effects and factors that change the effect of drugs, toxic effects of drugs and chemical substances and their treatments,
3) To act as a consultant on rational drug use and safe drug use, which are the basis of pharmaceutical care,
4) To have the ability to practice their profession within the framework of laws and regulations
5) Adhering to the principles of professional ethics and Deontology
6) To have national and international communication skills in the field
7) To have knowledge about health policies, health economics and pharmacy management
8) To be in effective communication with institutions and organizations in the field of health, the pharmaceutical industry and professional organizations
9) To have professional skills that adopt scientific and evidence-based lifelong learning
10) To have knowledge and skills in the field of basic sciences and health sciences related to medicine and pharmacy,
11) To be able to follow new developments in the field by using a foreign language,
12) To have the ability to think socially, culturally and intellectually,
13) To be an individual/pharmacist who knows Atatürk's principles and the history of the nation and is equipped with modern universal knowledge.
14) To have the ability to use Turkish correctly and to speak well,

Relationship Between Course and Learning Outcome

No Effect	1 Lowest	2 Low	3 Medium	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	To have knowledge and application skills about pre-formulation, formulation, laboratory, pilot and industrial scale production, quality assurance, quality control, validation, stability, storage, bioavailability, bioequivalence, licensing and patent studies of natural, synthetic, biological, biotechnological, nanotechnological, cosmetic, dermocosmetic products.
2)	To have basic information about diseases, the stages of all drugs in the body, their mechanism of action, undesirable effects and factors that change the effect of drugs, toxic effects of drugs and chemical substances and their treatments,
3)	To act as a consultant on rational drug use and safe drug use, which are the basis of pharmaceutical care,
4)	To have the ability to practice their profession within the framework of laws and regulations
5)	Adhering to the principles of professional ethics and Deontology
6)	To have national and international communication skills in the field
7)	To have knowledge about health policies, health economics and pharmacy management
8)	To be in effective communication with institutions and organizations in the field of health, the pharmaceutical industry and professional organizations
9)	To have professional skills that adopt scientific and evidence-based lifelong learning
10)	To have knowledge and skills in the field of basic sciences and health sciences related to medicine and pharmacy,
11)	To be able to follow new developments in the field by using a foreign language,
12)	To have the ability to think socially, culturally and intellectually,
13)	To be an individual/pharmacist who knows Atatürk's principles and the history of the nation and is equipped with modern universal knowledge.
14)	To have the ability to use Turkish correctly and to speak well,

Learning Activities and Teaching Methods

Anlatım
Beyin fırtınası /Altı şapka
Course
Problem Çözme
Soru cevap/ Tartışma
Web Tabanlı Öğrenme

Assessment and Evaluation Methods and Criteria

Yazılı Sınav (Açık uçlu sorular, çoktan seçmeli, doğru yanlış, eşleştirme, boşluk doldurma, sıralama)
Gözlem

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 45
Final	1	% 50
Kanaat Notu	1	% 5
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Workload
Course Hours	16	30
Study Hours Out of Class	16	20
Midterms	8	8
Final	16	16
Total Workload		74